Article
The v-src oncogene may not be responsible for the increased radioresistance of hematopoietic progenitor cells expressing v-src.
Radiation research - 1 Mar 1992
Santucci M A, Anklesaria P, Anderson S M, Das I J, FitzGerald T J, Valinsky H, Kase K R, Sakakeeny M A, Greenberger J S
Abstract excerpt
Infection of the IL-3-dependent, myeloid progenitor cell line 32D cl 3 with murine retroviruses that contain either the wild-type or a temperature-sensitive mutant v-src can render these cells growth-factor independent. These cells also became resistant to gamma irradiation administered at the low-dose rate of 0.05 Gy/min, which is used clinically. The v-src-dependent nature of resistance to gamma irradiation was...
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