Article
The LRRK2 Gly2385Arg variant is associated with Parkinson's disease: genetic and functional evidence.
Human genetics - 1 Feb 2007
Tan E K, Zhao Y, Skipper L, Tan M G, Di Fonzo A, Sun L, Fook-Chong S, Tang S, Chua E, Yuen Y, Tan L, Pavanni R, Wong M C, Kolatkar P, Lu C S, Bonifati V, Liu J J
Abstract excerpt
Evidence of LRRK2 haplotypes associated with Parkinson's disease (PD) risk was recently found in the Chinese population from Singapore, and a common LRRK2 missense variant, Gly2385Arg, was independently detected as a putative risk factor for PD in the Chinese population from Taiwan. To test the association between the Gly2385Arg variant in a large case-control sample of Chinese ethnicity from Singapore, and to...
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