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Analysis of the LRRK2 Gly2385Arg variant in Alzheimer's disease in Taiwan.

Parkinsonism & related disorders - 1 Jan 2010

Chang Ting-Yu, Kuo Hung-Chou, Lu Chin-Song, Wu-Chou Yah-Huei, Huang Chin-Chang

Abstract excerpt

OBJECTIVE: To analyze the Gly2385Arg (G2385R) mutation in Taiwanese Alzheimer's disease (AD) patients. BACKGROUND: The leucine-rich repeat kinase 2 (LRRK2) gene is well known to predispose subjects to Parkinson's disease (PD). The Gly2385Arg (G2385R) variant of LRRK2 is believed to be "East Asian"-specific, particularly in the Han Chinese population; however, whether the LRRK2 G2385R is associated with a risk of...

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PMID: 19640773
DOI: 10.1016/j.parkreldis.2009.06.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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