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Identification of a common genetic risk variant (LRRK2 Gly2385Arg) in Parkinson's disease.

Annals of the Academy of Medicine, Singapore - 1 Nov 2006

Tan Eng-King

Abstract excerpt

The recent identification of a common genetic variant (LRRK2 G2385R) which is associated with a two-fold increased risk of sporadic Parkinson's Disease (PD) in two independent Chinese populations in Singapore and Taiwan has generated considerable excitement. Thus far, this variant appears specific for the Asian population, emphasising further that ethnic-specific effects should be considered in genetic...

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PMID: 17160203

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