Article
Analysis of LRRK2 Gly2385Arg genetic variant in non-Chinese Asians.
Movement disorders : official journal of the Movement Disorder Society - 15 Sept 2007
Tan Eng-King, Zhao Yi, Tan Louis, Lim Hui-Qin, Lee Jasinda, Yuen Yih, Pavanni Ratnagopal, Wong Meng-Cheong, Fook-Chong Stephanie, Liu Jian-Jun
Abstract excerpt
A common LRRK2 missense variant, Gly2385Arg, has been found to be a genetic risk factor for Parkinson's disease (PD) in ethnic Chinese and Japanese. However, the presence of the variant in other non-Chinese Asian patients has not been fully clarified. We performed genetic analysis of the Gly2385Arg variant in 472 non-Chinese Asian subjects in Singapore (comprising of 166 PD and 306 controls of Malay/Indian...
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