Article
The prevalence of LRRK2 Gly2385Arg variant in Chinese Han population with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2007
Li Cao, Ting Zhang, Qin Xiao, Ying Wang, Li Bai, Guo Qiang Lu, Jian Fang Ma, Jing Zhang, Jian Qing Ding, Sheng Di Chen
Abstract excerpt
We conducted a case-control study to determine the prevalence of the LRRK2 Gly2385Arg variant in patients with Parkinson's disease in Han population in mainland China. Heterozygous LRRK2 Gly2385Arg variant was identified in 14 of 235 patients with Parkinson's disease (5.69%), but not in 214 unrelated healthy controls. Multivariate analysis indicated the frequency of Gly2385Arg variant in the female patients with...
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