Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association between the LRRK2 G2385R variant and the risk of Parkinson's disease: a meta-analysis based on 23 case-control studies.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Oct 2014

Xie Cheng-Long, Pan Jia-Lin, Wang Wen-Wen, Zhang Yu, Zhang Su-Fang, Gan Jing, Liu Zhen-Guo

Abstract excerpt

Clinical diagnosis of Parkinson's disease (PD) is essential but misdiagnosis of PD-like diseases is quite common. LRRK2 G2385R variants have been extensively examined for the association to the risk of Parkinson's disease. However, results from different studies are inconsistent. The purpose of this meta-analysis was to assess the association between the LRRK2 G2385R variants and the risk of PD. A systematic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Parkinson Disease

Share to Polymorphism, Genetic

Share to Protein Serine-Threonine Kinases

Share to Risk Factors

Source

Identifiers

PMID: 25027012
DOI: 10.1007/s10072-014-1878-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association between the LRRK2 G2385R variant and the risk of Parkinson's disease: a meta-analysis based on 23 case-control studies.PMID 25027012Read ↗

The association between the LRRK2 R1628P variant and the risk of Parkinson's disease in Asian: a meta-analysis.Semantic proximity Read ↗

The prevalence of LRRK2 Gly2385Arg variant in Chinese Han population with Parkinson's disease.Semantic proximity Read ↗

Correlation between LRRK2 gene G2385R polymorphisms and Parkinson's disease.Semantic proximity Read ↗

LRRK2 mutations and risk variants in Japanese patients with Parkinson's disease.Semantic proximity Read ↗

Quantitative assessment of the effect of LRRK2 exonic variants on the risk of Parkinson's disease: a meta-analysis.Semantic proximity Read ↗

Leucine-Rich Repeat Kinase (LRRK2) Genetics and Parkinson's Disease.Semantic proximity Read ↗

LRRK2 A419V variant is a risk factor for Parkinson's disease in Asian population.Semantic proximity Read ↗

LRRK2 G2385R variant carriers of female Parkinson's disease are more susceptible to motor fluctuation.Semantic proximity Read ↗

Effect of a Leucine-rich Repeat Kinase 2 Variant on Motor and Non-motor Symptoms in Chinese Parkinson’s Disease PatientsSemantic proximity Read ↗

Relationship between LRRK2 R1628P polymorphism and Parkinson's disease in Asian populations.Semantic proximity Read ↗

LRRK2 G2385R and LRRK2 R1628P increase risk of Parkinson's disease in a Han Chinese population from Southern Mainland ChinaSemantic proximity Read ↗

LRRK2 Pro755Leu variant in ethnic Chinese population with Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.