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Article

Restricted V-segment usage in T-cell receptors from cytotoxic T lymphocytes specific for a major epitope of lymphocytic choriomeningitis virus.

Journal of virology - 1 Dec 1990

Yanagi Y, Maekawa R, Cook T, Kanagawa O, Oldstone M B

Abstract excerpt

Cytotoxic T lymphocytes (CTL) play an important role in recovery from a number of viral infections. They are also implicated in virus-induced immunopathology as best demonstrated in lymphocytic choriomeningitis virus (LCMV) infection of adult immunocompetent mice. In the present study, the structure of the T-cell receptor (TCR) in LCMV-specific CTL in C57BL/6 (B6) mice was investigated. Spleen T cells obtained...

Topics

Amino Acid Sequence
Animals
Antigens, Viral
Base Sequence
Epitopes
Fluorescent Antibody Technique
Genetic Variation
Lymphocytic Choriomeningitis
Lymphocytic choriomeningitis virus
Macromolecular Substances

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice

Mice, Inbred C57BL

Molecular Sequence Data

Receptors, Antigen, T-Cell

Sequence Homology, Nucleic Acid

Spleen

T-Lymphocytes, Cytotoxic

Source

Open in PubMed Open full text

Identifiers

PMID: 1700830
DOI: 10.1128/JVI.64.12.5919-5926.1990
PMCID: PMC248763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1700830-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Restricted V-segment usage in T-cell receptors from cytotoxic T lymphocytes specific for a major epitope of lymphocytic choriomeningitis virus.PMID 1700830Read ↗

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