Article
Two distinct alpha beta T-cell lineages can be distinguished by the differential usage of T-cell receptor V beta gene segments.
Proceedings of the National Academy of Sciences of the United States of America - 1 Dec 1991
Lahti J M, Chen C L, Tjoelker L W, Pickel J M, Schat K A, Calnek B W, Thompson C B, Cooper M D
Abstract excerpt
Avian T cells can be divided into three subpopulations based on their expression of distinct T-cell receptors (TCR1, TCR2, and TCR3), ontogeny, and tissue distribution. The TCR1 cells appear to be the equivalent of mammalian gamma delta cells, but the derivation of cells expressing TCR2 and TCR3 has been unclear. Here we report that chickens contain two families of TCR beta variable (V) gene segments, V beta 1...
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