Article
The signal sequence of lymphocytic choriomeningitis virus contains an immunodominant cytotoxic T cell epitope that is restricted by both H-2D(b) and H-2K(b) molecules.
Virology - 21 Jul 1997
Hudrisier D, Oldstone M B, Gairin J E
Abstract excerpt
Infection of H-2b mice with lymphocytic choriomeningitis virus (LCMV) generates three well-characterized H-2D(b)-restricted immunodominant epitopes delineated in the NP, GP1, and GP2 proteins. Here we report that the H-2D(b)-restricted GP1 epitope GP33-41/43 (KAVYNFATC/GI) located in the signal s...
Topics
- Alleles
- Animals
- Antigens, Viral
- Cell Line, Transformed
- Epitopes, T-Lymphocyte
- Glycoproteins
- H-2 Antigens
- Histocompatibility Antigen H-2D
- Humans
- Immunodominant Epitopes
- Leucine
- Lymphocytic choriomeningitis virus
- Major Histocompatibility Complex
- Mice
- Mice, Inbred BALB C
- Mutation
- Peptide Fragments
- Phenylalanine