Article
Stability and diversity of T cell receptor repertoire usage during lymphocytic choriomeningitis virus infection of mice.
The Journal of experimental medicine - 7 Dec 1998
Lin M Y, Welsh R M
Abstract excerpt
Numerous studies have examined T cell receptor (TCR) usage of selected virus-specific T cell clones, yet little information is available regarding the stability and diversity of TCR repertoire usage during viral infections. Here, we analyzed the Vbeta8.1 TCR repertoire directly ex vivo by complem...
Topics
- Animals
- CD8-Positive T-Lymphocytes
- Cytotoxicity, Immunologic
- Genetic Variation
- Immunoglobulin Variable Region
- Lymphocyte Activation
- Lymphocytic Choriomeningitis
- Lymphocytic choriomeningitis virus
- Male
- Mice
- Mice, Inbred C57BL
- Receptors, Antigen, T-Cell
- T-Lymphocyte Subsets