Article
T cell receptor-gamma allele-specific selection of V gamma 1/V delta 4 cells in the intestinal epithelium.
Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2002
Grigoriadou Kalliopi, Boucontet Laurent, Pereira Pablo
Abstract excerpt
Previous genetic analyses have shown that the relative representation of subsets of gammadelta intestinal intraepithelial lymphocytes (i-IELs) is influenced by genes linked to the TCRgamma, TCRdelta, and MHC loci. Here, we have analyzed V-gene use in gammadelta i-IELs from C57BL/6 (B6) and C57BL/10 (B10) mice and from their F(1) and F(2) progenies with a larger panel of Vgamma- and Vdelta-specific mAbs and have...
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