Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oncogene‐specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis†

27 Sept 2006

Abstract excerpt

We applied a genome-wide microarray analysis to three transgenic mouse models of liver cancer in which targeted overexpression of c-Myc, E2f1, and a combination of the two was driven by the albumin promoter. Although gene expression profiles in HCC derived in all three transgenic lines were highly similar, oncogene-specific gene expression signatures were identified at an early dysplastic stage of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cancer-related Molecular Pathways
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17006931
DOI: 10.1002/hep.21293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oncogene‐specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis†PMID 17006931Read ↗

Global gene expression in Ha-ras and B-raf mutated mouse liver tumors.Semantic proximity Read ↗

Global gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancer.Semantic proximity Read ↗

Distinct and shared synergistic effects of high-fat and high-iron diets on liver tumorigenesis and transcriptomic remodeling in miceSemantic proximity Read ↗

Disruption of beta-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice.Semantic proximity Read ↗

Human-correlated genetic models identify precision therapy for liver cancer.Semantic proximity Read ↗

Human-correlated genetic HCC models identify combination therapy for precision medicineSemantic proximity Read ↗

Genomic progression in mouse models for liver tumors.Semantic proximity Read ↗

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach.Semantic proximity Read ↗

Comparative functional genomics for identifying models of human cancerSemantic proximity Read ↗

Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.Semantic proximity Read ↗

Integrative genomic analysis of mouse and human hepatocellular carcinomaSemantic proximity Read ↗

Diet-induced hepatocellular carcinoma in genetically predisposed mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.