Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diet-induced hepatocellular carcinoma in genetically predisposed mice.

Human molecular genetics - 15 Aug 2009

Hill-Baskin Annie E, Markiewski Maciej M, Buchner David A, Shao Haifeng, DeSantis David, Hsiao Gene, Subramaniam Shankar, Berger Nathan A, Croniger Colleen, Lambris John D, Nadeau Joseph H

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death worldwide, with approximately 70% of cases resulting from hepatitis B and C viral infections, aflatoxin exposure, chronic alcohol use or genetic liver diseases. The remaining approximately 30% of cases are associated with obesity, type 2 diabetes and related metabolic diseases, although a direct link between these pathologies and HCCs has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Dietary Fats

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Liver Neoplasms

Share to Mice, Inbred A

Share to Mice, Inbred C57BL

Source

Open in PubMed Open full text

Identifiers

PMID: 19454484
DOI: 10.1093/hmg/ddp236
PMCID: PMC2714725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diet-induced hepatocellular carcinoma in genetically predisposed mice.PMID 19454484Read ↗

Integrative genomic analysis of mouse and human hepatocellular carcinomaSemantic proximity Read ↗

Nutrigenomics of High Fat Diet Induced Obesity in Mice Suggests Relationships between Susceptibility to Fatty Liver Disease and the ProteasomeSemantic proximity Read ↗

Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic TumorsSemantic proximity Read ↗

Differences in metabolic and liver pathobiology induced by two dietary mouse models of nonalcoholic fatty liver diseaseSemantic proximity Read ↗

Hepatocellular carcinoma in the context of non-alcoholic steatohepatitis (NASH): recent advances in the pathogenic mechanisms.Semantic proximity Read ↗

Hepatic immune environment differences among common mouse strains in models of MASH and liver cancerSemantic proximity Read ↗

The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in MiceSemantic proximity Read ↗

A new chemical carcinogen and Western diet protocol to reliably induce advanced hepatocellular carcinoma in male and female miceSemantic proximity Read ↗

Genetic and epigenetic changes in fibrosis‐associated hepatocarcinogenesis in miceSemantic proximity Read ↗

The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progressionSemantic proximity Read ↗

Genetically modified mouse models for the study of nonalcoholic fatty liver diseaseSemantic proximity Read ↗

A transgenic mouse model of steatosis and hepatocellular carcinoma associated with chronic hepatitis C virus infection in humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.