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Human-correlated genetic HCC models identify combination therapy for precision medicine

2022-05-12

Abstract excerpt

<title>Abstract</title> <p>Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, is a leading cause of cancer related mortality worldwide. HCC occurs typically from a background of chronic liver disease, caused by a spectrum of predisposing conditions. Tumour development is driven by the expansion of clones that accumulated progressive driver mutations, with hepatocytes the most likely cel...

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Literature Corpus work: 4675896f-b272-5ae2-93c0-dedf5d8fb51b
DOI: 10.21203/rs.3.rs-1638504/v1

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