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Article

Genomic progression in mouse models for liver tumors.

Cold Spring Harbor symposia on quantitative biology - 1 Jan 2005

Tward A D, Jones K D, Yant S, Kay M A, Wang R, Bishop J M

Abstract excerpt

The principal cause of human liver cancer is infection with hepatitis viruses B and C, but tumor progression is fueled by ensuing perturbations that confer gain of function on proto-oncogenes or loss of function on tumor suppressor genes. Frequent among these perturbations is overexpression of the proto-oncogene MET. We have modeled the pathogenesis of liver tumors by expressing conditional transgenes of MET in...

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Source

Identifiers

PMID: 16869757
DOI: 10.1101/sqb.2005.70.058

Genes

MET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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