Article
Involvement of helix 34 of 16 S rRNA in decoding and translocation on the ribosome.
The Journal of biological chemistry - 17 Nov 2006
Kubarenko Andrew, Sergiev Petr, Wintermeyer Wolfgang, Dontsova Olga, Rodnina Marina V
Abstract excerpt
Helix 34 of 16 S rRNA is located in the head of the 30 S ribosomal subunit close to the decoding center and has been invoked in a number of ribosome functions. In the present work, we have studied the effects of mutations in helix 34 both in vivo and in vitro. Several nucleotides in helix 34 that are either highly conserved or form important tertiary contacts in 16 S rRNA (U961, C1109, A1191, and A1201) were...
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