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Article

Genetic evidence against the 16S ribosomal RNA helix 27 conformational switch model.

RNA (New York, N.Y.) - 1 Jan 2004

Rodriguez-Correa Daniel, Dahlberg Albert E

Abstract excerpt

A mechanistic understanding of ribosome function demands knowledge of the conformational changes that occur during protein synthesis. One current model proposes a conformational switch in Helix 27 (H27) of 16S rRNA involved in the decoding of mRNA. This model was based on the behavior of mutations in the 912 region of H27 of Escherichia coli 16S rRNA, which were predicted to stabilize the helix in either of two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14681582
DOI: 10.1261/rna.5172104
PMCID: PMC1370515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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