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Article

Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome.

RNA (New York, N.Y.) - 1 Aug 2000

Velichutina I V, Dresios J, Hong J Y, Li C, Mankin A, Synetos D, Liebman S W

Abstract excerpt

A dynamic structural rearrangement in the phylogenetically conserved helix 27 of Escherichia coli 16S rRNA has been proposed to directly affect the accuracy of translational decoding by switching between "accurate" and "error-prone" conformations. To examine the function of helix 27 in eukaryotes, random and site-specific mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA have been...

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Identifiers

PMID: 10943896
DOI: 10.1017/s1355838200000637
PMCID: PMC1369991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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