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Article

Bases in 16S rRNA important for subunit association, tRNA binding, and translocation.

Biochemistry - 28 Jul 2009

Shi Xinying, Chiu Katie, Ghosh Srikanta, Joseph Simpson

Abstract excerpt

Ribosomes are the cellular machinery responsible for protein synthesis. A well-orchestrated step in the elongation cycle of protein synthesis is the precise translocation of the tRNA-mRNA complex within the ribosome. Here we report the application of a new in vitro modification-interference method for the identification of bases in 16S rRNA that are essential for translocation. Our results suggest that conserved...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19545171
DOI: 10.1021/bi900472a
PMCID: PMC2782751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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