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Article

Helix 69 in 23S rRNA modulates decoding by wild type and suppressor tRNAs.

Molecular genetics and genomics : MGG - 1 Oct 2009

O'Connor Michael

Abstract excerpt

Helix 69 of 23S rRNA forms one of the major inter-subunit bridges of the 70S ribosome and interacts with A- and P-site tRNAs and translation factors. Despite the proximity of h69 to the decoding center and tRNAs, the contribution of h69 to the tRNA selection process is unclear: previous genetic analyses have shown that h69 mutations increase frameshifting and readthrough of stop codons. However, a complete...

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Identifiers

PMID: 19603183
DOI: 10.1007/s00438-009-0470-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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