Mutations in helix 34 of Escherichia coli 16 S ribosomal RNA have multiple effects on ribosome function and synthesis.

doi:10.1006/jmbi.1994.1668

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Article

Mutations in helix 34 of Escherichia coli 16 S ribosomal RNA have multiple effects on ribosome function and synthesis.

Journal of molecular biology - 28 Oct 1994

Moine H, Dahlberg A E

Abstract excerpt

Helix 34 of E. coli 16 S rRNA (1046 to 1067 and 1189 to 1211) has been proposed to participate directly in the termination of translation at UGA stop codons. We have constructed mutations in this helix in plasmid-encoded rDNA to explore the specific functional roles of the sequence UCAUCA (1199 t...

Topics

Base Sequence
Codon, Terminator
Escherichia coli
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Protein Biosynthesis
RNA, Ribosomal, 16S
Ribosomes
beta-Galactosidase

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