Article
Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors.
The EMBO journal - 1 Oct 1990
Nocka K, Buck J, Levi E, Besmer P
Abstract excerpt
The c-kit proto-oncogene encodes a transmembrane tyrosine kinase receptor for an unidentified ligand and is allelic with the murine white-spotting locus (W). W mutations affect melanogenesis, gametogenesis and hematopoiesis during development and in adult life. Cellular targets of W mutations in...
Topics
- Alleles
- Animals
- Cell Division
- Cell Line
- Cells, Cultured
- Chromatography, Gel
- Chromatography, High Pressure Liquid
- Chromatography, Ion Exchange
- Fibroblast Growth Factors
- Hematopoietic Stem Cells
- Isoelectric Focusing
- Ligands
- Mast Cells
- Mice
- Mice, Inbred BALB C