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Article

Allelic loss of Hox11L1 gene locus predicts outcome of gastrointestinal stromal tumors.

Oncology reports - 1 Oct 2006

Kaifi Jussuf T, Wagner Meike, Schurr Paulus G, Wachowiak Robin, Reichelt Uta, Yekebas Emre F, Mann Oliver, Vashist Yogesh, Kleinhans Helge, Link Bjoern-Christian, Strate Tim, Kalinin Viacheslav, Izbicki Jakob R

Abstract excerpt

Loss of heterozygosity (LOH) in tumors has been described to have prognostic impact. Hox11L1 gene, located on chromosome 2, has a role in proliferation of neuronal myenteric Cajal cells being the progenitor cells of GISTs. The aim was to examine the frequency and prognostic value of allelic loss of Hox11L1 gene locus in GISTs. Tumor and control DNA of 72 GIST patients was extracted after microdissection from...

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PMID: 16969514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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