Article
Restriction fragment length polymorphism analysis reveals different allele frequency and a linkage disequilibrium at locus D1S94 in neuroblastoma patients.
European journal of cancer (Oxford, England : 1990) - 1 Oct 1997
Perri P, Pession A, Mazzocco K, Scaruffi P, Strigini P, Iolascon A, Albergoni M P, Basso G, Tonini G P
Abstract excerpt
Deletion of chromosome 1p and MYCN amplification have been reported as frequent abnormalities in human neuroblastoma. We studied loss of heterozygosity (LOH) in 50 (48 informative) Italian neuroblastoma patients by restriction fragment length polymorphisms (RFLPs) analysis using anonymous and hyp...
Topics
- Alleles
- Chromosomes, Human, Pair 1
- Gene Amplification
- Genes, myc
- Genetic Linkage
- Genetics, Population
- Humans
- Italy
- Loss of Heterozygosity
- Neuroblastoma
- Polymorphism, Restriction Fragment Length
- Prognosis