Article
Microsatellite DNA alterations of gastrointestinal stromal tumors are predictive for outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2006
Schurr Paulus, Wolter Stefan, Kaifi Jussuf, Reichelt Uta, Kleinhans Helge, Wachowiak Robin, Yekebas Emre, Strate Tim, Kalinin Viacheslav, Simon Ronald, Sauter Guido, Schaefer Hansjoerg, Izbicki Jakob
Abstract excerpt
PURPOSE: In gastrointestinal stromal tumors (GIST), loss of heterozygosity (LOH) on chromosome 22 and its presumptive biological function has been described. The prognostic value of these and other DNA regions for patient survival remains unclear. EXPERIMENTAL DESIGN: Sixty patients who underwent surgery at our institution between 1992 and 2003 for GIST were histopathologically reclassified by...
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