Microallelotyping defines novel regions of loss of heterozygosity in uterine leiomyomas.

doi:10.1002/mc.20074

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Microallelotyping defines novel regions of loss of heterozygosity in uterine leiomyomas.

Molecular carcinogenesis - 1 Mar 2005

Canevari Renata de Azevedo, Pontes Anaglória, Rogatto Silvia Regina

Abstract excerpt

Uterine leiomyomas are extremely common, benign, smooth muscle tumors that represent a significant public health problem. Although there have been few molecular studies of uterine leiomyomas, most of them have reported a very low frequency of loss of heterozygosity (LOH) in different regions of the genome. The detection of LOH has been used to identify genomic regions that harbor tumor suppressor genes and to...

Topics

Alleles
Case-Control Studies
Chromosomes, Human, Pair 7
Female
Genes, Tumor Suppressor
Genetic Markers
Humans
Leiomyoma
Loss of Heterozygosity
Microsatellite Repeats
Polymorphism, Genetic
Uterine Neoplasms

Source

Open in PubMed

Identifiers

PMID: 15605361
DOI: 10.1002/mc.20074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics