Article
Prognostic value of chromosome 1p allelic loss in colon cancer.
Gastroenterology - 1 Sept 1997
Ogunbiyi O A, Goodfellow P J, Gagliardi G, Swanson P E, Birnbaum E H, Fleshman J W, Kodner I J, Moley J F
Abstract excerpt
BACKGROUND & AIMS: Current evidence suggests that there may be a tumor-suppressor gene on chromosome 1p associated with colorectal cancer. The aim of the present study was to determine whether allelic loss on chromosome 1p is of prognostic value in colorectal cancer. METHODS: Polymerase chain reaction was used to assess allelic loss of five chromosome 1p microsatellite markers in tumor specimens. Genomic DNA was...
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