Fractional allelic loss in gastric carcinoma correlates with growth patterns.

doi:10.1038/sj.onc.1202188

Back to search

Article

Fractional allelic loss in gastric carcinoma correlates with growth patterns.

Oncogene - 19 Nov 1998

Choi S W, Park S W, Lee K Y, Kim K M, Chung Y J, Rhyu M G

Abstract excerpt

To gain an insight into the genetic events underlying morphological phenotypes, we analysed 58 gastric carcinoma tissues for the genome-wide allelotype study using microsatellite markers. Based on a binomial distribution, loss of heterozygosity (LOH) that was significantly more frequent than expe...

Topics

Adenocarcinoma
Adenocarcinoma, Mucinous
Alleles
Carcinoma, Papillary
Carcinoma, Signet Ring Cell
Cell Division
DNA, Neoplasm
Gene Deletion
Genetic Markers
Humans
Loss of Heterozygosity
Microsatellite Repeats
Phenotype
Polymerase Chain Reaction
Stomach Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.