Article
Loss of heterozygosity identifies multiple sites of allelic deletions on chromosome 1 in human male germ cell tumors.
Cancer research - 1 Dec 1994
Mathew S, Murty V V, Bosl G J, Chaganti R S
Abstract excerpt
Cytogenetic analysis of human male germ cell tumors (GCTs) and derived cell lines revealed frequent deletions and rearrangements of chromosome 1. However, no detailed molecular analysis of these aberrations has thus far been performed. We undertook loss of heterozygosity (LOH) analysis utilizing...
Topics
- Alleles
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Genetic Markers
- Germinoma
- Humans
- Male
