Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of heterozygosity identifies multiple sites of allelic deletions on chromosome 1 in human male germ cell tumors.

Cancer research - 1 Dec 1994

Mathew S, Murty V V, Bosl G J, Chaganti R S

Abstract excerpt

Cytogenetic analysis of human male germ cell tumors (GCTs) and derived cell lines revealed frequent deletions and rearrangements of chromosome 1. However, no detailed molecular analysis of these aberrations has thus far been performed. We undertook loss of heterozygosity (LOH) analysis utilizing a panel of 48 GCTs at 22 subregionally mapped polymorphic loci on both arms of chromosome 1. Eight probes, for which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosome Deletion
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 1

Share to Genetic Markers

Share to Germinoma

Source

Identifiers

PMID: 7954476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of heterozygosity identifies multiple sites of allelic deletions on chromosome 1 in human male germ cell tumors.PMID 7954476Read ↗

Loss of heterozygosity on chromosome arms 5q, 11p, 11q, 13q, and 16p in human testicular germ cell tumors.Semantic proximity Read ↗

BCL10 is not a major target for frequent loss of 1p in testicular germ cell tumors.Semantic proximity Read ↗

Frequent loss of heterozygosity at 11p loci in testicular cancer.Semantic proximity Read ↗

Pooled analysis of loss of heterozygosity in breast cancer: a genome scan provides comparative evidence for multiple tumor suppressors and identifies novel candidate regions.Semantic proximity Read ↗

Allelic loss on chromosome 1p is Associated with progression and lymph node metastasis of primary breast carcinomaSemantic proximity Read ↗

Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors.Semantic proximity Read ↗

Identification of a consistent region of allelic loss on 1p32 in meningiomas: correlation with increased morbidity.Semantic proximity Read ↗

Frequent loss of heterozygosity at 6q in pheochromocytoma.Semantic proximity Read ↗

A genome-wide map showing common regions of loss of heterozygosity/allelic imbalance in breast cancer.Semantic proximity Read ↗

Large-Scale Allelotype of Pancreaticobiliary Carcinoma Provides Quantitative Estimates of Genome-Wide Allelic LossSemantic proximity Read ↗

Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10Semantic proximity Read ↗

Frequent clonal loss of heterozygosity (LOH) in the chromosomal region 1p32 occurs in childhood T cell acute lymphoblastic leukemia (T-ALL) carrying rearrangements of the TAL1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.