Article
Genome-wide association study of loss of heterozygosity and metastasis-free survival in breast cancer patients.
Experimental oncology - 1 Jul 2017
Deryusheva I V, Tsyganov M, Garbukov E Y, Ibragimova M K, Kzhyshkovska Ju G, Slonimskaya E, Cherdyntseva N V, Litviakov N V
Abstract excerpt
One of the factors providing the diversity and heterogeneity of malignant tumors, particularly breast cancer, are genetic variations, due to gene polymorphism, and, especially, the phenomenon of loss of heterozygosity (LOH). It has been shown that LOH in some genes could be a good prognostic marker. AIM: To perform genome-wide study on LOH in association with metastasis-free survival in breast cancer. MATERIALS...
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