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Article

Multiplex locked nucleic acid probes for analysis of hepatitis B virus mutants using real-time PCR.

Genomics - 1 Jan 2007

Sun Zhen, Zhou Linfu, Zeng Haiyan, Chen Zhi, Zhu Haihong

Abstract excerpt

Current methods of detecting hepatitis B virus (HBV) mutations are time consuming, labor intensive, and not suitable for screening large numbers of samples. A multiplex real-time PCR approach presented in this article is a hepatitis B virus quantification method that employs the SYBR Green I dye in conjunction with wild-type HBV sequence-specific locked nucleic acid (LNA) probes. The three short LNA probes...

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Identifiers

PMID: 16935466
DOI: 10.1016/j.ygeno.2006.07.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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