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Article

Hepatitis B virus quantification and detection of YMDD mutants in a single reaction by real-time PCR and annealing curve analysis.

Antiviral therapy - 1 Jan 2008

Shih Yi-Hsien, Yeh Shiou-Hwei, Chen Pei-Jer, Chou Wen-Pin, Wang Hurng-Yi, Liu Chun-Jen, Lu Su-Feng, Chen Ding-Shinn

Abstract excerpt

BACKGROUND: Long-term antiviral therapy, although effective for treatment of hepatitis B, might select the emergence of drug-resistant hepatitis B virus (HBV) mutants. Detection of HBV mutants and determination of viral titre are two crucial parameters for monitoring treatment response and occurrence of mutants. In this study, we take lamivudine resistance as an example to develop a method that can determine both...

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PMID: 18672526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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