Article
Soluble guanylyl cyclase activation promotes angiogenesis.
The Journal of pharmacology and experimental therapeutics - 1 Nov 2006
Pyriochou Anastasia, Beis Dimitris, Koika Vasiliki, Potytarchou Christos, Papadimitriou Evangelia, Zhou Zongmin, Papapetropoulos Andreas
Abstract excerpt
Soluble guanylyl cyclase (sGC) is a cGMP-generating enzyme carrying a heme prosthetic group that functions as a nitric oxide (NO) sensor. sGC is present in most cells types, including the vascular endothelium, where its biological functions remain largely unexplored. Herein, we have investigated...
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