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Article

Soluble guanylate cyclases act in neurons exposed to the body fluid to promote C. elegans aggregation behavior.

Current biology : CB - 22 Jun 2004

Cheung Benny H H, Arellano-Carbajal Fausto, Rybicki Irene, de Bono Mario

Abstract excerpt

The genome of the nematode Caenorhabditis elegans encodes seven soluble guanylate cyclases (sGCs). In mammals, sGCs function as alpha/beta heterodimers activated by gaseous ligands binding to a haem prosthetic group. The principal activator is nitric oxide, which acts through sGCs to regulate diverse cellular events. In C. elegans the function of sGCs is mysterious: the worm genome does not appear to encode...

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PMID: 15203005
DOI: 10.1016/j.cub.2004.06.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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