Article
Gas6 stimulates angiogenesis of human retinal endothelial cells and of zebrafish embryos via ERK1/2 signaling.
PloS one - 1 Jan 2014
Kim Young Sook, Jung Seung-Hyun, Jung Dong Ho, Choi So-Jin, Lee Yu-Ri, Kim Jin Sook
Abstract excerpt
AIM: To determine if growth arrest-specific 6 (Gas6) plays an important role in the regulation of angiogenesis in human retinal microvascular endothelial cells (HRMECs) and in vessel development of zebrafish. METHODS: Proliferation, wound-healing cell migration, and tube formation were measured in HRMECs treated with recombinant human Gas6 (rhGas6). Sprague-Dawley rat aortas in Matrigels were treated with rhGas6,...
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