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Article

Pleiotrophin expression and role in physiological angiogenesis in vivo: potential involvement of nucleolin

1 Jan 2012

Abstract excerpt

BACKGROUND: Pleiotrophin (PTN) is a heparin-binding growth factor with significant role(s) in tumour growth and angiogenesis. Although implication of endogenous PTN has been studied in several in vivo models of tumour angiogenesis, its role in physiological angiogenesis has not been addressed. In the present work, we studied expression and functional significance of endogenous PTN during angiogenesis in the...

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PMID: 22423616
DOI: 10.1186/2045-824x-4-4

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