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Article

Hypoxia induces downregulation of soluble guanylyl cyclase β1 by miR-34c-5p

5 Oct 2012

Abstract excerpt

Soluble guanylyl cyclase (sGC) is the principal receptor for nitric oxide (NO) and crucial for the control of various physiological functions. The β1 subunit of sGC is obligatory for the biological stability and activity of the sGC heterodimer. MicroRNAs (miRNAs) are important regulators of gene expression and exert great influences on diverse biological activities. The aim of the present study was to determine...

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PMID: 23038777
DOI: 10.1242/jcs.113381

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