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Article

Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients.

Journal of gastroenterology - 1 Jul 2006

Umeoka Fumi, Iwasaki Yoshiaki, Matsumura Masayuki, Takaki Akinobu, Kobashi Haruhiko, Tatsukawa Masashi, Shiraha Hidenori, Fujioka Shin-ichi, Sakaguchi Kohsaku, Shiratori Yasushi

Abstract excerpt

BACKGROUND: Long-term lamivudine treatment induces the emergence of lamivudine-resistant hepatitis B virus (HBV). The objective of this study was to develop a fluorescent biprobe hybridization (FBH) assay for the detection and quantification of HBV mutants in the clinical course of lamivudine-tre...

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Identifiers

PMID: 16933008
DOI: 10.1007/s00535-006-1834-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16933008-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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