Article
Long-term effects of lamivudine treatment in Japanese chronic hepatitis B patients.
World journal of gastroenterology - 28 Jun 2011
Murata Masayuki, Furusyo Norihiro, Unno Mami, Ogawa Eiichi, Toyoda Kazuhiro, Taniai Hiroaki, Ohnishi Hachiro, Hayashi Jun
Abstract excerpt
AIM: To analyze the association between the emergence of tyrosine-methionine-asparatate-asparatate (YMDD) mutants (reverse transcription; rtM204I/V) and deterioration of liver function during long-term lamivudine treatment of Japanese patients with chronic hepatitis B virus (HBV) infection. METHODS: The data of 61 consecutive Japanese patients with chronic hepatitis B who underwent continuous lamivudine treatment...
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