Article
Clinical evaluation of oligonucleotide microarrays for the detection of HBV mutants associated with lamivudine resistance.
Pharmacogenomics - 1 Oct 2005
Chen Li-Yan, Huang Jian, Zhang Xin-Ping, Qiao Ping, Zhang Wen, Yang Ning-Min, Liu Hong-Jing, Geng Yong-Yao, Qiu Jian-Ming, Wang Sheng-Qi
Abstract excerpt
OBJECTIVES: Long-term lamivudine administration in hepatitis B virus (HBV)-infected patients induces the emergence of HBV mutants with lamivudine resistance. The aim of the present study was to evaluate the clinical application of an oligonucleotide microarray in detecting HBV mutants associated with lamivudine resistance. METHODS: 947 HBV DNA-positive sera from: 388 patients receiving lamivudine treatment, 559...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
