Article
Quantification of the relative levels of wild-type and lamivudine-resistant mutant virus in serum of HBV-infected patients using microarray.
Journal of viral hepatitis - 1 Mar 2005
Li Z G, Chen L Y, Huang J, Qiao P, Qiu J M, Wang S Q
Abstract excerpt
During the course of lamivudine administration in hepatitis B virus (HBV)-infected patients, a dynamic development of the viral population in serum is observed. Total HBV level is initially reduced, then lamivudine-resistant mutants appear, and finally, the viral level is increased. All methods of mutant detection so far described can only identify mutants in the serum, and cannot determine the proportion of...
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