Article
A real-time quantitative polymerase chain reaction method for hepatitis B virus in patients with chronic hepatitis B treated with lamivudine.
The American journal of gastroenterology - 1 Sept 2003
Ide Tatsuya, Kumashiro Ryukichi, Koga Yuriko, Tanaka Eisuke, Hino Teruko, Hisamochi Akiko, Murashima Shiro, Ogata Kei, Tanaka Kazuo, Kuwahara Reiichiro, Sata Michio
Abstract excerpt
OBJECTIVES: During treatment of chronic hepatitis B with lamivudine, changes in the level of hepatitis B virus (HBV) DNA were investigated using a real-time polymerase chain reaction (PCR) method with a detection limit of 1.7 log copies/ml (50 copies/ml) to clarify its clinical significance, part...
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