Article
Changes in the nuclear envelope environment affect spindle pole body duplication in Saccharomyces cerevisiae.
Genetics - 1 Nov 2010
Witkin Keren L, Friederichs Jennifer M, Cohen-Fix Orna, Jaspersen Sue L
Abstract excerpt
The Saccharomyces cerevisiae nuclear membrane is part of a complex nuclear envelope environment also containing chromatin, integral and peripheral membrane proteins, and large structures such as nuclear pore complexes (NPCs) and the spindle pole body. To study how properties of the nuclear membrane affect nuclear envelope processes, we altered the nuclear membrane by deleting the SPO7 gene. We found that spo7Δ...
Topics
- Alleles
- Gene Deletion
- Gene Dosage
- Genes, Suppressor
- Nuclear Envelope
- Phenotype
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Spindle Apparatus
- Suppression, Genetic