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Article

B cell chronic lymphocytic leukaemia/small lymphocytic lymphoma: role of ZAP70 determination on bone marrow biopsy specimens.

Journal of clinical pathology - 1 Jun 2007

Sabattini Elena, Orduz Rocio, Campidelli Cristina, Zinzani Pier Luigi, Callea Vincenzo, Zupo Simona, Cutrona Giovanna, Morabito Fortunato, Ferrarini Manlio, Pileri Stefano

Abstract excerpt

BACKGROUND: The course of chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL) partly depends on the mutational status of the variable region of immunoglobulin heavy chain genes (IgV(H)), which defines two subgroups of tumours: mutated and unmutated. The expression of zeta-associated protein 70 (ZAP70) is significantly associated with the more aggressive unmutated forms. AIMS: To assess the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Source

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Identifiers

PMID: 16916999
DOI: 10.1136/jcp.2006.039586
PMCID: PMC1955054

Genes

ZAP70

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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