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Article

Quantification of ZAP70 mRNA in B cells by real-time PCR is a powerful prognostic factor in chronic lymphocytic leukemia.

Clinical chemistry - 1 Oct 2007

Stamatopoulos Basile, Meuleman Nathalie, Haibe-Kains Benjamin, Duvillier Hughes, Massy Martine, Martiat Philippe, Bron Dominique, Lagneaux Laurence

Abstract excerpt

BACKGROUND: Chronic lymphocytic leukemia (CLL) is heterogeneous with respect to prognosis and clinical outcome. The mutational status of the immunoglobulin variable heavy chain region (IGHV) has been used to classify patients into 2 groups in terms of overall survival (OS) and clinical characteristics, but the labor-intensive nature and the cost of this time-consuming analysis has prompted investigations of...

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Share to ADP-ribosyl Cyclase 1
Share to Antigens, CD19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Lipoprotein Lipase

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Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 17702857
DOI: 10.1373/clinchem.2007.089326

Genes

ZAP70

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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