Article
Effects of interphase and mitotic phosphorylation on the mobility and location of nucleolar protein B23.
Journal of cell science - 1 Sept 2006
Negi Sandeep S, Olson Mark O J
Abstract excerpt
B23 (or nucleophosmin, NPM) is a multifunctional protein involved in ribosome biogenesis, control of centrosome duplication and in sensing cellular stress. It is phosphorylated during interphase by casein kinase 2 (CK2) and during mitosis by cyclin-dependent kinase (CDK). In this study we have addressed the role of these phosphorylation events in the dynamics and location of protein B23. Mutation of the CK2...
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