Article
Regulation of nucleolar chromatin by B23/nucleophosmin jointly depends upon its RNA binding activity and transcription factor UBF.
Molecular and cellular biology - 1 Oct 2010
Hisaoka Miharu, Ueshima Shuhei, Murano Kensaku, Nagata Kyosuke, Okuwaki Mitsuru
Abstract excerpt
Histone chaperones regulate the density of incorporated histone proteins around DNA transcription sites and therefore constitute an important site-specific regulatory mechanism for the control of gene expression. At present, the targeting mechanism conferring this site specificity is unknown. We previously reported that the histone chaperone B23/nucleophosmin associates with rRNA chromatin (r-chromatin) to...
Topics
- Base Sequence
- Binding Sites
- CDC2 Protein Kinase
- Cell Cycle
- Cell Line
- Cell Nucleolus
- Chromatin
- Cyclin B
- Cyclin-Dependent Kinases
- DNA Primers
- HeLa Cells