Article
Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress.
Journal of cell science - 1 Oct 2004
Lindqvist Arne, Källström Helena, Karlsson Rosenthal Christina
Abstract excerpt
Cdc25 phosphatases are essential regulators of the cell cycle. In mammalian cells, the Cdc25B isoform activates cyclin A- and cyclin B1-containing complexes and is necessary for entry into mitosis. In this report, we characterise the subcellular localisation of Cdc25B by immunofluorescence in combination with RNA interference to identify specific antibody staining. We find that endogenous Cdc25B is mainly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
