Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

B23 and ARF: friends or foes?

Cell biochemistry and biophysics - 1 Jan 2006

Lindström Mikael S, Zhang Yanping

Abstract excerpt

B23 (nucleophosmin/NPM) is a multifunctional protein that recently has been directly implicated in the p53 network by its documented interaction with the p14(ARF)/p19(Arf) tumor suppressor, a major upstream activator of p53. Here we provide an overview of the functional interactions of B23 and ARF. We also integrate the current models into a unified picture, showing that B23 is essential for stabilizing and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleolus
Share to Neoplasms
Share to Nuclear Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nucleophosmin

Share to Proto-Oncogene Proteins c-mdm2

Share to Translocation, Genetic

Share to Tumor Suppressor Protein p14ARF

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 16943625
DOI: 10.1385/CBB:46:1:79

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

B23 and ARF: friends or foes?PMID 16943625Read ↗

Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival.Semantic proximity Read ↗

Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23.Semantic proximity Read ↗

NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingSemantic proximity Read ↗

It’s Getting Complicated—A Fresh Look at p53-MDM2-ARF Triangle in Tumorigenesis and Cancer TherapySemantic proximity Read ↗

DNA Damage Disrupts the p14ARF-B23(Nucleophosmin) Interaction and Triggers a Transient Subnuclear Redistribution of p14ARFSemantic proximity Read ↗

Myeloid Leukemia-Associated Nucleophosmin Mutants Perturb p53-Dependent and Independent Activities of the Arf Tumor Suppressor ProteinSemantic proximity Read ↗

The Myc-Nucleophosmin-ARF network: A complex web unveiledSemantic proximity Read ↗

The RNA binding activity of a ribosome biogenesis factor, nucleophosmin/B23, is modulated by phosphorylation with a cell cycle-dependent kinase and by association with its subtype.Semantic proximity Read ↗

Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant.Semantic proximity Read ↗

A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth.Semantic proximity Read ↗

Mechanisms of TP53 Pathway Inactivation in Embryonic and Somatic Cells—Relevance for Understanding (Germ Cell) TumorigenesisSemantic proximity Read ↗

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.